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WHSC1 is involved in DNA damage, cellular senescence and immune response in hepatocellular carcinoma progression
Wolf–Hirschhorn syndrome candidate 1 (WHSC1) is a transcriptional regulatory protein that encodes a histone methyltransferase to control H3K36me2 modification. WHSC1 was upregulated and associated with poor prognosis in HCC. The elevated WHSC1 likely due to the alterations of DNA methylation or RNA...
Autores principales: | Yan, Jia, Zhang, Ming Yang, Lin, Jing, Li, Ke Xin, Zhao, Zhi Min, Gao, Yu Min, Deng, Xiu Ling, Wang, Chang Shan, Wang, Hai Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183708/ https://www.ncbi.nlm.nih.gov/pubmed/37073435 http://dx.doi.org/10.1111/jcmm.17743 |
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