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Lamin Filament Assembly Derived from the Atomic Structure of the Antiparallel Four-Helix Bundle

The nucleoskeletal protein lamin is primarily responsible for the mechanical stability of the nucleus. The lamin assembly process requires the A11, A22, and ACN binding modes of the coiled-coil dimers. Although X-ray crystallography and chemical cross-linking analysis of lamin A/C have provided snap...

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Detalles Bibliográficos
Autores principales: Ahn, Jinsook, Jo, Inseong, Jeong, Soyeon, Lee, Jinwook, Ha, Nam-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183791/
https://www.ncbi.nlm.nih.gov/pubmed/37170772
http://dx.doi.org/10.14348/molcells.2023.2144