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The Role of Pyruvate Metabolism in Mitochondrial Quality Control and Inflammation

Pyruvate metabolism, a key pathway in glycolysis and oxidative phosphorylation, is crucial for energy homeostasis and mitochondrial quality control (MQC), including fusion/fission dynamics and mitophagy. Alterations in pyruvate flux and MQC are associated with reactive oxygen species accumulation an...

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Detalles Bibliográficos
Autores principales: Kim, Min-Ji, Lee, Hoyul, Chanda, Dipanjan, Thoudam, Themis, Kang, Hyeon-Ji, Harris, Robert A., Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183795/
https://www.ncbi.nlm.nih.gov/pubmed/36756776
http://dx.doi.org/10.14348/molcells.2023.2128