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Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns

Recruitment of RNA polymerase II (Pol II) to promoters is essential for transcription. Despite conflicting evidence, the Pol II preinitiation complex (PIC) is often thought to have a uniform composition and to assemble at all promoters via an identical mechanism. Here, using Drosophila melanogaster...

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Detalles Bibliográficos
Autores principales: Serebreni, Leonid, Pleyer, Lisa‐Marie, Haberle, Vanja, Hendy, Oliver, Vlasova, Anna, Loubiere, Vincent, Nemčko, Filip, Bergauer, Katharina, Roitinger, Elisabeth, Mechtler, Karl, Stark, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183819/
https://www.ncbi.nlm.nih.gov/pubmed/37013908
http://dx.doi.org/10.15252/embj.2023113519