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Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies

Cancer cells display persistent underlying chromosomal instability, with individual tumour types intriguingly exhibiting characteristic subsets of whole, and subchromosomal aneuploidies. Few methods to induce specific aneuploidies will exist, hampering investigation of functional consequences of rec...

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Detalles Bibliográficos
Autores principales: Tovini, Laura, Johnson, Sarah C, Guscott, Molly A, Andersen, Alexander M, Spierings, Diana Carolina Johanna, Wardenaar, René, Foijer, Floris, McClelland, Sarah E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183824/
https://www.ncbi.nlm.nih.gov/pubmed/37063065
http://dx.doi.org/10.15252/embj.2022111587