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Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies
Cancer cells display persistent underlying chromosomal instability, with individual tumour types intriguingly exhibiting characteristic subsets of whole, and subchromosomal aneuploidies. Few methods to induce specific aneuploidies will exist, hampering investigation of functional consequences of rec...
Autores principales: | Tovini, Laura, Johnson, Sarah C, Guscott, Molly A, Andersen, Alexander M, Spierings, Diana Carolina Johanna, Wardenaar, René, Foijer, Floris, McClelland, Sarah E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183824/ https://www.ncbi.nlm.nih.gov/pubmed/37063065 http://dx.doi.org/10.15252/embj.2022111587 |
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