Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment

Nucleophosmin (NPM1) is frequently mutated in acute myeloid leukemia, and NPM1 expression is elevated in several cancer types. NPM1 is a multifunctional oligomeric protein involved in numerous cellular functions that include participating in liquid–liquid phase separation, ribosome biogenesis, chape...

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Detalles Bibliográficos
Autores principales: Sekhar, Konjeti R., Freeman, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183826/
https://www.ncbi.nlm.nih.gov/pubmed/36877156
http://dx.doi.org/10.1158/0008-5472.CAN-22-3631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183826/
https://www.ncbi.nlm.nih.gov/pubmed/36877156
http://dx.doi.org/10.1158/0008-5472.CAN-22-3631

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