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Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment

Nucleophosmin (NPM1) is frequently mutated in acute myeloid leukemia, and NPM1 expression is elevated in several cancer types. NPM1 is a multifunctional oligomeric protein involved in numerous cellular functions that include participating in liquid–liquid phase separation, ribosome biogenesis, chape...

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Detalles Bibliográficos
Autores principales:	Sekhar, Konjeti R., Freeman, Michael L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183826/ https://www.ncbi.nlm.nih.gov/pubmed/36877156 http://dx.doi.org/10.1158/0008-5472.CAN-22-3631

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