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Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors

Considering the varied pharmacological prominence of thiazole and oxadiazole heterocyclic moieties, a unique series of bi-heterocyclic hybrids, 8a–h, was synthesized in a convergent manner. The structures of newly synthesized compounds were characterized by (1)H-NMR, (13)C-NMR, and IR spectral studi...

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Detalles Bibliográficos
Autores principales: Butt, Abdul Rehman Sadiq, Abbasi, Muhammad Athar, Aziz-ur-Rehman, Siddiqui, Sabahat Zahra, Muhammad, Shabbir, Raza, Hussain, Shah, Syed Adnan Ali, Shahid, Muhammad, Alsehemi, Abdullah G., Kim, Song Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184136/
https://www.ncbi.nlm.nih.gov/pubmed/37197574
http://dx.doi.org/10.1039/d3ra01348k