Cargando…

Modular One-Pot Strategy for the Synthesis of Heterobivalent Tracers

[Image: see text] Bivalent ligands, i.e., molecules having two ligands covalently connected by a linker, have been gathering attention since the first description of their pharmacological potential in the early 80s. However, their synthesis, particularly of labeled heterobivalent ligands, can still...

Descripción completa

Detalles Bibliográficos
Autores principales: Bailly, Thibaud, Bodin, Sacha, Goncalves, Victor, Denat, Franck, Morgat, Clément, Prignon, Aurélie, Valverde, Ibai E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184157/
https://www.ncbi.nlm.nih.gov/pubmed/37197474
http://dx.doi.org/10.1021/acsmedchemlett.3c00057