Metastatic clear-cell renal cell carcinoma: a frequent NOTCH1 mutation predictive of response to anti-NOTCH1 CB-103 treatment

BACKGROUND: Clear-cell renal cell carcinomas (ccRCCs) are malignant tumors with high metastatic potential and resistance to treatments occurs almost constantly. Compared to primary tumors, there are still limited genomic data that has been obtained from metastatic samples. METHODS: We aimed to chara...

Descripción completa

Detalles Bibliográficos
Autores principales: Bui, Thi Oanh, Angeli, Eurydice, El Bouchtaoui, Morad, Gapihan, Guillaume, Dao, Van Tu, Paris, Justine, Leboeuf, Christophe, Soussan, Michael, Villarese, Patrick, Ziol, Marianne, Van Glabeke, Emmanuel, Le, Thi Huong, Feugeas, Jean-Paul, Janin, Anne, Bousquet, Guilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184347/
https://www.ncbi.nlm.nih.gov/pubmed/37189165
http://dx.doi.org/10.1186/s40164-023-00408-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184347/
https://www.ncbi.nlm.nih.gov/pubmed/37189165
http://dx.doi.org/10.1186/s40164-023-00408-z

Ejemplares similares