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Single-cell RNA sequencing reveals the vascular smooth muscle cell phenotypic landscape in aortic aneurysm

BACKGROUND AND OBJECTIVES: Phenotypic switching in vascular smooth muscle cells (VSMCs) has been linked to aortic aneurysm, but the phenotypic landscape in aortic aneurysm is poorly understood. The present study aimed to analyse the phenotypic landscape, phenotypic differentiation trajectory, and po...

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Detalles Bibliográficos
Autores principales: Cao, Genmao, Xuan, Xuezhen, Li, Yaling, Hu, Jie, Zhang, Ruijing, Jin, Haijiang, Dong, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184349/
https://www.ncbi.nlm.nih.gov/pubmed/37189183
http://dx.doi.org/10.1186/s12964-023-01120-5