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Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation

Rheumatoid arthritis (RA) is characterized by bone destruction in the afflicted joints, and during the process of bone destruction, osteoclasts play a crucial role. Tanshinone IIA (Tan IIA) has shown anti-inflammatory effects in RA. However, the exact molecular mechanisms by which it delays bone des...

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Detalles Bibliográficos
Autores principales: Peng, Qiuwei, Wang, Jian, Han, Man, Zhao, Minghong, Li, Kesong, Lu, Tianming, Guo, Qiuyan, Jiang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184368/
https://www.ncbi.nlm.nih.gov/pubmed/37189204
http://dx.doi.org/10.1186/s13020-023-00765-1