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Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation
Rheumatoid arthritis (RA) is characterized by bone destruction in the afflicted joints, and during the process of bone destruction, osteoclasts play a crucial role. Tanshinone IIA (Tan IIA) has shown anti-inflammatory effects in RA. However, the exact molecular mechanisms by which it delays bone des...
Autores principales: | Peng, Qiuwei, Wang, Jian, Han, Man, Zhao, Minghong, Li, Kesong, Lu, Tianming, Guo, Qiuyan, Jiang, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184368/ https://www.ncbi.nlm.nih.gov/pubmed/37189204 http://dx.doi.org/10.1186/s13020-023-00765-1 |
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