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Nerve injury increases native Ca(V)2.2 trafficking in dorsal root ganglion mechanoreceptors

Neuronal N-type (Ca(V)2.2) voltage-gated calcium channels are essential for neurotransmission from primary afferent terminals in the dorsal horn. In this study, we have used a knockin mouse containing Ca(V)2.2 with an inserted extracellular hemagglutinin tag (Ca(V)2.2_HA), to visualise the pattern o...

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Detalles Bibliográficos
Autores principales: Nieto-Rostro, Manuela, Patel, Ryan, Dickenson, Anthony H., Dolphin, Annette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184561/
https://www.ncbi.nlm.nih.gov/pubmed/36524581
http://dx.doi.org/10.1097/j.pain.0000000000002846