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EPRS1 Controls the TGF-β Signaling Pathway via Interaction with TβRI in Hepatic Stellate Cell

Glutamyl-prolyl-tRNA synthetase 1 (EPRS1) is known to associated with fibrosis through its catalytic activity to produce prolyl-tRNA. Although its catalytic inhibitor halofuginone (HF) has been known to inhibit the TGF-β pathway as well as to reduce prolyl-tRNA production for the control of fibrosis...

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Detalles Bibliográficos
Autores principales: Yoon, Ina, Song, Ji Ae, Suh, Ji Hun, Kim, Sulhee, Son, Jonghyeon, Kim, Jong Hyun, Jang, Song Yee, Hwang, Kwang Yeon, Kim, Myung Hee, Kim, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184599/
https://www.ncbi.nlm.nih.gov/pubmed/37154023
http://dx.doi.org/10.1080/10985549.2023.2205344