M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistance

T-cell-based immune checkpoint blockade therapy (ICB) can be undermined by local immunosuppressive M2-like tumor-associated macrophages (TAMs). However, modulating macrophages has proved difficult as the molecular and functional features of M2-TAMs on tumor growth are still uncertain. Here we report...

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Detalles Bibliográficos
Autores principales: Zheng, Naisheng, Wang, Tingting, Luo, Qin, Liu, Yi, Yang, Junyao, Zhou, Yunlan, Xie, Guohua, Ma, Yanhui, Yuan, Xiangliang, Shen, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184604/
https://www.ncbi.nlm.nih.gov/pubmed/37197441
http://dx.doi.org/10.1080/2162402X.2023.2210959

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