M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistance
T-cell-based immune checkpoint blockade therapy (ICB) can be undermined by local immunosuppressive M2-like tumor-associated macrophages (TAMs). However, modulating macrophages has proved difficult as the molecular and functional features of M2-TAMs on tumor growth are still uncertain. Here we report...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184604/ https://www.ncbi.nlm.nih.gov/pubmed/37197441 http://dx.doi.org/10.1080/2162402X.2023.2210959 |