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Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells

BACKGROUND: Cisplatin-based chemotherapy is frequently used to treat advanced gastric cancer (GC). However, the resistance often occurs with the mechanisms being not well understood. Recently, emerging evidence indicates that tumor-associated macrophages (TAMs) play an important role in chemoresista...

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Detalles Bibliográficos
Autores principales: Zheng, Peiming, Chen, Lei, Yuan, Xiangliang, Luo, Qin, Liu, Yi, Xie, Guohua, Ma, Yanhui, Shen, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390430/
https://www.ncbi.nlm.nih.gov/pubmed/28407783
http://dx.doi.org/10.1186/s13046-017-0528-y