Patient-Specific iPSC-Derived Models Link Aberrant Endoplasmic Reticulum Stress Sensing and Response to Juvenile Osteochondritis Dissecans Etiology

Juvenile osteochondritis dissecans (JOCD) is a pediatric disease, which begins with an osteonecrotic lesion in the secondary ossification center which, over time, results in the separation of the necrotic fragment from the parent bone. JOCD predisposes to early-onset osteoarthritis. However, the kno...

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Detalles Bibliográficos
Autores principales: Salazar-Noratto, Giuliana E, Nations, Catriana C, Stevens, Hazel Y, Xu, Maojia, Gaynard, Sean, Dooley, Claire, de Nijs, Nica, McDonagh, Katya, Shen, Sanbing, Willimon, S Clifton, Barry, Frank, Guldberg, Robert E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184700/
https://www.ncbi.nlm.nih.gov/pubmed/37184892
http://dx.doi.org/10.1093/stcltm/szad018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184700/
https://www.ncbi.nlm.nih.gov/pubmed/37184892
http://dx.doi.org/10.1093/stcltm/szad018

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