Cargando…
Mechanisms that promote the evolution of cross-reactive antibodies upon vaccination with designed influenza immunogens
Immunogens that elicit broadly neutralizing antibodies targeting the conserved receptor-binding site (RBS) on influenza hemagglutinin may serve as candidates for a universal influenza vaccine. Here, we develop a computational model to interrogate antibody evolution by affinity maturation after immun...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184763/ https://www.ncbi.nlm.nih.gov/pubmed/36867533 http://dx.doi.org/10.1016/j.celrep.2023.112160 |