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Cinchonine, a Potential Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist, Lowers Blood Glucose and Ameliorates Non-Alcoholic Steatohepatitis

PURPOSE: The glucagon-like peptide-1 receptor (GLP-1R) is an effective therapeutic target for type 2 diabetes mellitus (T2DM) and non-alcoholic steatohepatitis (NASH). Research has focused on small-molecule GLP-1R agonists because of their ease of use in oral formulations and improved patient compli...

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Detalles Bibliográficos
Autores principales: Xue, Huan, Xing, Hao-Jie, Wang, Bin, Fu, Chao, Zhang, Yu-Shan, Qiao, Xi, Guo, Chao, Zhang, Xiao-Li, Hu, Bin, Zhao, Xin, Deng, Li-Jiao, Zhu, Xiao-Chan, Zhang, Yi, Liu, Yun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184894/
https://www.ncbi.nlm.nih.gov/pubmed/37197367
http://dx.doi.org/10.2147/DDDT.S404055