Cargando…

Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are anti-hyperglycemic agents that prevent glucose reabsorption in proximal tubular cells. SGLT2i improves renal outcomes in both diabetic and non-diabetic patients, indicating it may have beneficial effects beyond glycemic control. Here, we demonst...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Mengyuan, Molina, Judith, Kim, Jin-Ju, Mallela, Shamroop K, Ahmad, Anis, Varona Santos, Javier, Al-Ali, Hassan, Mitrofanova, Alla, Sharma, Kumar, Fontanesi, Flavia, Merscher, Sandra, Fornoni, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185338/
https://www.ncbi.nlm.nih.gov/pubmed/37129368
http://dx.doi.org/10.7554/eLife.83353