High-resolution structures with bound Mn(2+) and Cd(2+) map the metal import pathway in an Nramp transporter

Transporters of the Nramp (Natural resistance-associated macrophage protein) family import divalent transition metal ions into cells of most organisms. By supporting metal homeostasis, Nramps prevent diseases and disorders related to metal insufficiency or overload. Previous studies revealed that Nr...

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Detalles Bibliográficos
Autores principales: Ray, Shamayeeta, Berry, Samuel P, Wilson, Eric A, Zhang, Casey H, Shekhar, Mrinal, Singharoy, Abhishek, Gaudet, Rachelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185341/
https://www.ncbi.nlm.nih.gov/pubmed/37039477
http://dx.doi.org/10.7554/eLife.84006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185341/
https://www.ncbi.nlm.nih.gov/pubmed/37039477
http://dx.doi.org/10.7554/eLife.84006

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