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Nr2f1a maintains atrial nkx2.5 expression to repress pacemaker identity within venous atrial cardiomyocytes of zebrafish

Maintenance of cardiomyocyte identity is vital for normal heart development and function. However, our understanding of cardiomyocyte plasticity remains incomplete. Here, we show that sustained expression of the zebrafish transcription factor Nr2f1a prevents the progressive acquisition of ventricula...

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Detalles Bibliográficos
Autores principales: Martin, Kendall E, Ravisankar, Padmapriyadarshini, Beerens, Manu, MacRae, Calum A, Waxman, Joshua S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185342/
https://www.ncbi.nlm.nih.gov/pubmed/37184369
http://dx.doi.org/10.7554/eLife.77408