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Cancer resistance via the downregulation of the tumor suppressors RKIP and PTEN expressions: therapeutic implications

The Raf kinase inhibitor protein (RKIP) has been reported to be underexpressed in many cancers and plays a role in the regulation of tumor cells' survival, proliferation, invasion, and metastasis, hence, a tumor suppressor. RKIP also regulates tumor cell resistance to cytotoxic drugs/cells. Lik...

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Detalles Bibliográficos
Autores principales: Moghaddam, Matthew, Vivarelli, Silvia, Falzone, Luca, Libra, Massimo, Bonavida, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185445/
https://www.ncbi.nlm.nih.gov/pubmed/37205308
http://dx.doi.org/10.37349/etat.2023.00128