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Cancer resistance via the downregulation of the tumor suppressors RKIP and PTEN expressions: therapeutic implications
The Raf kinase inhibitor protein (RKIP) has been reported to be underexpressed in many cancers and plays a role in the regulation of tumor cells' survival, proliferation, invasion, and metastasis, hence, a tumor suppressor. RKIP also regulates tumor cell resistance to cytotoxic drugs/cells. Lik...
Autores principales: | Moghaddam, Matthew, Vivarelli, Silvia, Falzone, Luca, Libra, Massimo, Bonavida, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Open Exploration
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185445/ https://www.ncbi.nlm.nih.gov/pubmed/37205308 http://dx.doi.org/10.37349/etat.2023.00128 |
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