Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids

Dietary mono-unsaturated fatty acids (MUFAs) are linked to longevity in several species. But the mechanisms by which MUFAs extend lifespan remain unclear. Here we show that an organelle network involving lipid droplets and peroxisomes is critical for MUFA-induced longevity in Caenorhabditis elegans....

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Detalles Bibliográficos
Autores principales: Papsdorf, Katharina, Miklas, Jason W., Hosseini, Amir, Cabruja, Matias, Morrow, Christopher S., Savini, Marzia, Yu, Yong, Silva-García, Carlos G., Haseley, Nicole R., Murphy, Luke Meraz, Yao, Pallas, de Launoit, Elisa, Dixon, Scott J., Snyder, Michael P., Wang, Meng C., Mair, William B., Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185472/
https://www.ncbi.nlm.nih.gov/pubmed/37127715
http://dx.doi.org/10.1038/s41556-023-01136-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185472/
https://www.ncbi.nlm.nih.gov/pubmed/37127715
http://dx.doi.org/10.1038/s41556-023-01136-6

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