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IGF2BP3 promotes adult myocardial regeneration by stabilizing MMP3 mRNA through interaction with m6A modification

Myocardial infarction that causes damage to heart muscle can lead to heart failure. The identification of molecular mechanisms promoting myocardial regeneration represents a promising strategy to improve cardiac function. Here we show that IGF2BP3 plays an important role in regulating adult cardiomy...

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Detalles Bibliográficos
Autores principales: Li, Simeng, Shen, Siman, Xu, Hao, Cai, Shuyun, Yuan, Xiaodong, Wang, Changsen, Zhang, Xiaojun, Chen, Suyun, Chen, Jianning, Shi, De-Li, Zhang, Liangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185520/
https://www.ncbi.nlm.nih.gov/pubmed/37188676
http://dx.doi.org/10.1038/s41420-023-01457-3