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Mutational signatures association with replication timing in normal cells reveals similarities and differences with matched cancer tissues
Mutational signatures’ association with replication timing (RT) has been studied in cancer samples, but the RT distribution of somatic mutations in non-cancerous cells was only minimally explored. Here, we performed comprehensive analyses of mutational signatures in 2.9 million somatic mutations acr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185532/ https://www.ncbi.nlm.nih.gov/pubmed/37188696 http://dx.doi.org/10.1038/s41598-023-34631-9 |