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Implications of genetic variations, differential gene expression, and allele-specific expression on metformin response in drug-naïve type 2 diabetes

PURPOSE: Metformin is widely used to treat type 2 diabetes mellitus (T2DM) individuals. Clinically, inter-individual variability of metformin response is of significant concern and is under interrogation. In this study, a targeted exome and whole transcriptome analysis were performed to identify pre...

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Detalles Bibliográficos
Autores principales: Vohra, M., Sharma, A. R., Mallya, S., Prabhu, N. B., Jayaram, P., Nagri, S. K., Umakanth, S., Rai, P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185588/
https://www.ncbi.nlm.nih.gov/pubmed/36528847
http://dx.doi.org/10.1007/s40618-022-01989-y