Development and testing of a polygenic risk score for breast cancer aggressiveness

Aggressive breast cancers portend a poor prognosis, but current polygenic risk scores (PRSs) for breast cancer do not reliably predict aggressive cancers. Aggressiveness can be effectively recapitulated using tumor gene expression profiling. Thus, we sought to develop a PRS for the risk of recurrenc...

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Detalles Bibliográficos
Autores principales: Shieh, Yiwey, Roger, Jacquelyn, Yau, Christina, Wolf, Denise M., Hirst, Gillian L., Swigart, Lamorna Brown, Huntsman, Scott, Hu, Donglei, Nierenberg, Jovia L., Middha, Pooja, Heise, Rachel S., Shi, Yushu, Kachuri, Linda, Zhu, Qianqian, Yao, Song, Ambrosone, Christine B., Kwan, Marilyn L., Caan, Bette J., Witte, John S., Kushi, Lawrence H., ‘T Veer, Laura van, Esserman, Laura J., Ziv, Elad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185660/
https://www.ncbi.nlm.nih.gov/pubmed/37188791
http://dx.doi.org/10.1038/s41698-023-00382-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185660/
https://www.ncbi.nlm.nih.gov/pubmed/37188791
http://dx.doi.org/10.1038/s41698-023-00382-z

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