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Age-related elevation of O-GlcNAc causes meiotic arrest in male mice

In recent years, the postponement of childbearing has become a critical social issue. Male fertility is negatively associated with age because of testis aging. Spermatogenesis is impaired with age, but the molecular mechanism remains unknown. The dynamic posttranslational modification O-linked N-ace...

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Detalles Bibliográficos
Autores principales: Qian, Zhang, Li, Chuwei, Zhao, Shanmeizi, Zhang, Hong, Ma, Rujun, Ge, Xie, Jing, Jun, Chen, Li, Ma, Jinzhao, Yang, Yang, Zheng, Lu, Zhang, Kemei, He, Zhaowanyue, Xue, Mengqi, Lin, Ying, Jueraitetibaike, Kadiliya, Feng, Yuming, Cao, Chun, Tang, Ting, Sun, Shanshan, Teng, Hui, Zhao, Wei, Yao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185674/
https://www.ncbi.nlm.nih.gov/pubmed/37188682
http://dx.doi.org/10.1038/s41420-023-01433-x