PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization

PARP2 is a member of the PARP enzyme family. Although, PARP2 plays role in DNA repair, it has regulatory roles in mitochondrial and lipid metabolism, it has pivotal role in bringing about the adverse effects of pharmacological PARP inhibitors. Previously, we showed that the ablation of PARP2 induces...

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Detalles Bibliográficos
Autores principales: Jankó, Laura, Tóth, Emese, Laczik, Miklós, Rauch, Boglárka, Janka, Eszter, Bálint, Bálint L., Bai, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185692/
https://www.ncbi.nlm.nih.gov/pubmed/37188809
http://dx.doi.org/10.1038/s41598-023-35076-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185692/
https://www.ncbi.nlm.nih.gov/pubmed/37188809
http://dx.doi.org/10.1038/s41598-023-35076-w

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