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PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization
PARP2 is a member of the PARP enzyme family. Although, PARP2 plays role in DNA repair, it has regulatory roles in mitochondrial and lipid metabolism, it has pivotal role in bringing about the adverse effects of pharmacological PARP inhibitors. Previously, we showed that the ablation of PARP2 induces...
Autores principales: | Jankó, Laura, Tóth, Emese, Laczik, Miklós, Rauch, Boglárka, Janka, Eszter, Bálint, Bálint L., Bai, Péter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185692/ https://www.ncbi.nlm.nih.gov/pubmed/37188809 http://dx.doi.org/10.1038/s41598-023-35076-w |
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