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Disentangling the effects of obesity and high-fat diet on glucose homeostasis using a photoperiod induced obesity model implicates ectopic fat deposition as a key factor

OBJECTIVE: Obesity in laboratory rodents is generally induced by feeding them a high fat diet (HFD). This model does not permit separation of the impact of the HFD from the resultant obesity on metabolic defects such as impaired glucose homeostasis. In Brandt's voles we have previously shown th...

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Detalles Bibliográficos
Autores principales: Yang, Deng Bao, Gao, Lin, Liu, Xin Yu, Xu, Yan Chao, Hambly, C., Wang, De Hua, Speakman, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185741/
https://www.ncbi.nlm.nih.gov/pubmed/37061130
http://dx.doi.org/10.1016/j.molmet.2023.101724