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Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity

The human protein tyrosine phosphatase non-receptor type 3 (PTPN3) is a phosphatase containing a PDZ (PSD-95/Dlg/ZO-1) domain that has been found to play both tumor-suppressive and tumor-promoting roles in various cancers, despite limited knowledge of its cellular partners and signaling functions. N...

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Detalles Bibliográficos
Autores principales: Genera, Mariano, Colcombet-Cazenave, Baptiste, Croitoru, Anastasia, Raynal, Bertrand, Mechaly, Ariel, Caillet, Joël, Haouz, Ahmed, Wolff, Nicolas, Caillet-Saguy, Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185773/
https://www.ncbi.nlm.nih.gov/pubmed/37200868
http://dx.doi.org/10.3389/fmolb.2023.1192621