FAT10 and NUB1L cooperate to activate the 26S proteasome

The interaction of the 19S regulatory particle of the 26S proteasome with ubiquitylated proteins leads to gate opening of the 20S core particle and increases its proteolytic activity by binding of the ubiquitin chain to the inhibitory deubiquitylation enzyme USP14 on the 19S regulatory subunit RPN1....

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Detalles Bibliográficos
Autores principales: Brockmann, Florian, Catone, Nicola, Wünsch, Christine, Offensperger, Fabian, Scheffner, Martin, Schmidtke, Gunter, Aichem, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185811/
https://www.ncbi.nlm.nih.gov/pubmed/37188463
http://dx.doi.org/10.26508/lsa.202201463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185811/
https://www.ncbi.nlm.nih.gov/pubmed/37188463
http://dx.doi.org/10.26508/lsa.202201463

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