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FAT10 and NUB1L cooperate to activate the 26S proteasome
The interaction of the 19S regulatory particle of the 26S proteasome with ubiquitylated proteins leads to gate opening of the 20S core particle and increases its proteolytic activity by binding of the ubiquitin chain to the inhibitory deubiquitylation enzyme USP14 on the 19S regulatory subunit RPN1....
Autores principales: | Brockmann, Florian, Catone, Nicola, Wünsch, Christine, Offensperger, Fabian, Scheffner, Martin, Schmidtke, Gunter, Aichem, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185811/ https://www.ncbi.nlm.nih.gov/pubmed/37188463 http://dx.doi.org/10.26508/lsa.202201463 |
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