Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis

BACKGROUND: Notch signaling is critical for regulating the function of vascular endothelial cells (ECs). However, the effect of the intracellular domain of Notch1 (NICD) on EC injury in sepsis remains unclear. METHODS: We established a cell model of vascular endothelial dysfunction and induced sepsi...

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Detalles Bibliográficos
Autores principales: Liu, Tingyan, Zhang, Caiyan, Ying, Jiayun, Wang, Yaodong, Yan, Gangfeng, Zhou, Yufeng, Lu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185824/
https://www.ncbi.nlm.nih.gov/pubmed/37205094
http://dx.doi.org/10.3389/fimmu.2023.1134556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185824/
https://www.ncbi.nlm.nih.gov/pubmed/37205094
http://dx.doi.org/10.3389/fimmu.2023.1134556

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