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Cigarette smoke increases susceptibility of alveolar macrophages to SARS-CoV-2 infection through inducing reactive oxygen species-upregulated angiotensin-converting enzyme 2 expression

Alveolar macrophages (AMs) are the drivers of pulmonary cytokine storm in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to investigate clinical–regulatory factors for the entrance protein of SARS-CoV-2, angiotensin–converting enzyme 2 (ACE2) in AMs. Human A...

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Detalles Bibliográficos
Autores principales: Kuo, Chin-Wei, Su, Po-Lan, Huang, Tang-Hsiu, Lin, Chien-Chung, Chen, Chian-Wei, Tsai, Jeng-Shiuan, Liao, Xin-Min, Chan, Tzu-Yi, Shieh, Chi-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185955/
https://www.ncbi.nlm.nih.gov/pubmed/37193781
http://dx.doi.org/10.1038/s41598-023-34785-6