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Epithelial CST1 Promotes Airway Eosinophilic Inflammation in Asthma via the AKT Signaling Pathway

PURPOSE: Epithelial cystatin SN (CST1), a type 2 cysteine protease inhibitor, was significantly upregulated in asthma. In this study, we aimed to investigate the potential role and mechanism of CST1 in eosinophilic inflammation in asthma. METHODS: Bioinformatics analysis on Gene Expression Omnibus d...

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Detalles Bibliográficos
Autores principales: Du, Lijuan, Xu, Changyi, Tang, Kun, Shi, Jia, Tang, Lu, Lisha, Xiao, Lei, Chengcheng, Liu, Huicong, Liang, Yuxia, Guo, Yubiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186126/
https://www.ncbi.nlm.nih.gov/pubmed/37075800
http://dx.doi.org/10.4168/aair.2023.15.3.374