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Non-parametric modelling of temporal and spatial counts data from RNA-seq experiments

MOTIVATION: The negative binomial distribution has been shown to be a good model for counts data from both bulk and single-cell RNA-sequencing (RNA-seq). Gaussian process (GP) regression provides a useful non-parametric approach for modelling temporal or spatial changes in gene expression. However,...

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Detalles Bibliográficos
Autores principales: BinTayyash, Nuha, Georgaka, Sokratia, John, S T, Ahmed, Sumon, Boukouvalas, Alexis, Hensman, James, Rattray, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186154/
https://www.ncbi.nlm.nih.gov/pubmed/34213536
http://dx.doi.org/10.1093/bioinformatics/btab486