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PD-1 limits differentiation and plasticity of Tc17 cells

Blockade of surface co-inhibitory receptor programmed cell death-1 (PD-1; CD279) has been established as an important immunotherapeutic approach to treat malignancies. On a cellular level, PD-1 is demonstrated to be of particular importance in inhibiting differentiation and effector function of cyto...

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Detalles Bibliográficos
Autores principales: Arra, Aditya, Lingel, Holger, Pierau, Mandy, Brunner-Weinzierl, Monika C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186197/
https://www.ncbi.nlm.nih.gov/pubmed/37205114
http://dx.doi.org/10.3389/fimmu.2023.1104730