Protocol of a Phase II Randomized, Multi-Center, Double-Blind, Placebo-Controlled Trial of S-Adenosyl Methionine in Participants with Mild Cognitive Impairment or Dementia Due to Alzheimer’s Disease

BACKGROUND: S-adenosyl methionine (SAMe) is a pivotal metabolite in multiple pathways required for neuronal homeostasis, several of which are compromised in Alzheimer’s disease (AD). Correction of the SAMe deficiency that is characteristic of the AD brain may attenuate or prevent pathological proces...

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Detalles Bibliográficos
Autores principales: Holper, Sarah, Watson, R., Churilov, L., Yates, P., Lim, Y. Y., Barnham, K. J., Yassi, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186290/
https://www.ncbi.nlm.nih.gov/pubmed/37874102
http://dx.doi.org/10.14283/jpad.2023.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186290/
https://www.ncbi.nlm.nih.gov/pubmed/37874102
http://dx.doi.org/10.14283/jpad.2023.55

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