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A self-binding immune complex vaccine elicits strong neutralizing responses against herpes simplex virus in mice

INTRODUCTION: It has been known for over half a century that mixing an antigen with its cognate antibody in an immune complex (IC) can enhance antigen immunogenicity. However, many ICs produce inconsistent immune responses, and the use of ICs in the development new vaccines has been limited despite...

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Detalles Bibliográficos
Autores principales: Diamos, Andrew G., Pardhe, Mary D., Bergeman, Melissa H., Kamzina, Aigerim S., DiPalma, Michelle P., Aman, Sara, Chaves, Artemio, Lowe, Kenneth, Kilbourne, Jacquelyn, Hogue, Ian B., Mason, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186352/
https://www.ncbi.nlm.nih.gov/pubmed/37205110
http://dx.doi.org/10.3389/fimmu.2023.1085911