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Rapid extraction and analysis of oxidative stress and DNA damage biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG) in urine: Application to a study with pregnant women

Oxidative stress is an important toxicity and genotoxicity mechanism of many chronic adverse health outcomes. This study developed a sensitive extraction method for urine matrix (based on lyophilization, without the need for pre-cleaning by solid phase extraction), coupled to LC-MS/MS analysis of th...

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Detalles Bibliográficos
Autores principales: Bláhová, Lucie, Janoš, Tomáš, Mustieles, Vicente, Rodríguez-Carrillo, Andrea, Fernández, Mariana F., Bláha, Luděk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Urban & Fischer 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186372/
https://www.ncbi.nlm.nih.gov/pubmed/37105016
http://dx.doi.org/10.1016/j.ijheh.2023.114175