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Rapid extraction and analysis of oxidative stress and DNA damage biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG) in urine: Application to a study with pregnant women
Oxidative stress is an important toxicity and genotoxicity mechanism of many chronic adverse health outcomes. This study developed a sensitive extraction method for urine matrix (based on lyophilization, without the need for pre-cleaning by solid phase extraction), coupled to LC-MS/MS analysis of th...
Autores principales: | Bláhová, Lucie, Janoš, Tomáš, Mustieles, Vicente, Rodríguez-Carrillo, Andrea, Fernández, Mariana F., Bláha, Luděk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Urban & Fischer
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186372/ https://www.ncbi.nlm.nih.gov/pubmed/37105016 http://dx.doi.org/10.1016/j.ijheh.2023.114175 |
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