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Effect of a 12-week high-intensity exercise intervention: a comparison of cardiac exercise adaptations during biological disease-modifying antirheumatic drug treatment (TNF inhibitors vs IL-6 signalling inhibitors) in patients with rheumatoid arthritis – study protocol for a randomised controlled trial

INTRODUCTION: The chronic inflammatory state in rheumatoid arthritis (RA) augments the risk of cardiovascular disease (CVD), with pro-inflammatory cytokines tumour necrosis factor (TNF) and interleukin 6 (IL-6) playing a vital role. Consequently, biological disease-modifying antirheumatic drugs (bDM...

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Detalles Bibliográficos
Autores principales: Jønck, Simon, Adamsen, Malte Lund, Højgaard, Pil, Rasmussen, Iben Elmerdahl, Ellingsgaard, Helga, Lund, Morten Asp Vonsild, Jørgensen, Peter Godsk, Jacobsen, Søren, Køber, Lars, Vejlstrup, Niels, Dreyer, Lene, Pedersen, Bente Klarlund, Berg, Ronan M G, Christensen, Regitse Højgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186416/
https://www.ncbi.nlm.nih.gov/pubmed/37169504
http://dx.doi.org/10.1136/bmjopen-2022-068600