Current allele distribution of the human longevity gene APOE in Europe can mainly be explained by ancient admixture

Variation in apolipoprotein E (APOE) has been shown to have the strongest genetic effect on human longevity. The aim of this study was to unravel the evolutionary history of the three major APOE alleles in Europe by analysing ancient samples up to 12,000 years old. We detected significant allele fre...

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Detalles Bibliográficos
Autores principales: Kolbe, Daniel, da Silva, Nicolas A., Dose, Janina, Torres, Guillermo G., Caliebe, Amke, Krause‐Kyora, Ben, Nebel, Almut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186601/
https://www.ncbi.nlm.nih.gov/pubmed/36951219
http://dx.doi.org/10.1111/acel.13819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186601/
https://www.ncbi.nlm.nih.gov/pubmed/36951219
http://dx.doi.org/10.1111/acel.13819

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